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// item · risk of rain 2

Lysate Cell, in depth.

Void item (purple). What the game says, what it really does, what each copy adds and what it pairs with.

// what it does

What it does.

Lysate Cell
Void item (purple)

Your special skill (R) gets one more use. Turns your Fuel Cells into this. Each extra one, another use.

Game text: «Add +1 (+1 per stack) charge of your Special skill. Corrupts all Fuel Cells.»

Stacking: Each copy adds the same, no cap.

Watch out: It also lowers the special cooldown (the game does not say so).

It is the void version of Fuel Cell: pick it up and every copy of that item turns into this one.

// per copy

What each copy adds.

1 copy2 copies3 copies5 copies10 copies
123510

Each copy adds the same.

// pairs with

What it pairs with.

Loader

two pylons or two slams.

Mercenary

two Eviscerates in a row.

Artificer

two Flamethrowers.

// how to get it

How to get it.

Found in Void Cradles, Encrusted Key caches, the Simulacrum and Void Locus. Never from a normal chest.

Unlocked from the start: it can show up in any run.

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// faq

FAQ.

What does Lysate Cell do in Risk of Rain 2?

Your special skill (R) gets one more use. Turns your Fuel Cells into this. Each extra one, another use.

What happens if you pick up several Lysate Cell?

Stacking: Each copy adds the same, no cap.Watch out: It also lowers the special cooldown (the game does not say so).

How do you get Lysate Cell?

Found in Void Cradles, Encrusted Key caches, the Simulacrum and Void Locus. Never from a normal chest. Unlocked from the start: it can show up in any run.

// more items

Other items in depth.

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Items in depth · Every item by rarity

Sources: the game's English text (name and description), the Risk of Rain 2 wiki (riskofrain2.wiki.gg: this item's page, read on 31 October 2026; numbers, stacking formula and notes) and the wiki's survivor pages. The plain-words text and the synergies are ours. Icons: Risk of Rain 2 (Hopoo Games / Gearbox).