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// item · risk of rain 2

Dio's Best Friend, in depth.

Legendary item (red). What the game says, what it really does, what each copy adds and what it pairs with.

// what it does

What it does.

Dio's Best Friend
Legendary item (red)

An extra life: if you die, you come back with 3 seconds of being untouchable. It is used up.

Game text: «Upon death, this item will be consumed and you will return to life with 3 seconds of invulnerability.»

Stacking: One extra life per copy; used up on revive.

It has a void version: Pluripotent Larva. Pick that up and every copy of this item turns into it.

// per copy

What each copy adds.

1 copy2 copies3 copies5 copies10 copies
123510

Each copy adds the same.

// pairs with

What it pairs with.

Pluripotent Larva

its void version: on revive, all your items get corrupted.

Artifact of Glass

with 10% health, the extra life is the difference.

// how to get it

How to get it.

Drops from legendary chests and, less often, from large and small chests.

Needs unlocking first with the challenge «The Lone Survivor».

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// faq

FAQ.

What does Dio's Best Friend do in Risk of Rain 2?

An extra life: if you die, you come back with 3 seconds of being untouchable. It is used up.

What happens if you pick up several Dio's Best Friend?

Stacking: One extra life per copy; used up on revive.

How do you get Dio's Best Friend?

Drops from legendary chests and, less often, from large and small chests. Needs unlocking first with the challenge «The Lone Survivor».

// more items

Other items in depth.

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Items in depth · Every item by rarity

Sources: the game's English text (name and description), the Risk of Rain 2 wiki (riskofrain2.wiki.gg: this item's page, read on 31 October 2026; numbers, stacking formula and notes) and the wiki's survivor pages. The plain-words text and the synergies are ours. Icons: Risk of Rain 2 (Hopoo Games / Gearbox).