Teleporter bosses, special bosses and final bosses. Each one with its attacks in plain words, how to dodge them and what it drops.
They appear when you start a stage's teleporter. Beating them drops items for the whole team.
Beetle Queen: Queen of the beetles: spits acid up close and calls her guards.
Stone Titan: A slow stone giant: what kills you is the eye laser.
Wandering Vagrant: A giant floating jellyfish that every so often blows up.
Clay Dunestrider: A pot on legs that throws clay balls and drains your life.
Grovetender: The wisp shepherd: releases a swarm that chases you and pulls you in with chains.
Imp Overlord: Lord of the imps: teleports and hits very hard up close.
Magma Worm: A huge lava worm that swims underground and burns you on contact.
Overloading Worm: The electric Magma Worm: five times the health and five times the damage. Only shows up at very high difficulty.
Solus Control Unit: A floating robot that fires orbs, launches probes and blows you into the air.
Grandparent: A seated giant that never moves: throws rocks and, below half health, lights a sun.
Scavenger: A slow hoarder that carries real items and keeps looking for more.
Xi Construct: A floating golden cube with a cannon and a bubble that blocks shots.
Void Devastator: The void giant: sticks white bombs to the floor and sets them off with a black one.
Solus Amalgamator: A robot made of other robots: as it loses health, pieces fall off and fight on their own.
Alloy Hunter: The Alloy Hunter of Conduit Canyon: she arrives mid-fight and kills the boss that was there.
Lynx Totem: The lynx totem: leaps, raises spires that heal it and sacrifices its allies.
Shruum: A giant mushroom that plants mushrooms, cages you and bursts out of the ground.
Each in its own place: a hidden realm, an event or an expansion route.
Alloy Worship Unit: The strong version of the Solus Control Unit. Only found in Siren's Call, and beating it unlocks Loader.
Aurelionite: A golden titan with a sword, guardian of the Gilded Coast.
Artifact Reliquary: The sphere that holds each artifact in the Artifact Trials. It only takes damage from keys.
Solus Wing: The big boss of Solutional Haunt (Alloyed Collective): it cannot move sideways and barely takes damage.
Anima Harvester: The boss of the Soulbound Threshold ritual (Hallowed Concepts): two phases, and winning ends Catastrophes for the run.
Echo of Providence: The echo of Providence, the first Risk of Rain's final boss and Mithrix's brother (Hallowed Concepts). Four phases.
The ones that end (or can end) the run.
Mithrix: The final boss: four pillars, four phases and escaping the moon.
Twisted Scavenger: The boss of A Moment, Whole: one of four lunar scavengers, each with a fixed set of items.
Voidling: The void final boss (Survivors of the Void): a three-phase fight with a chase in between.
False Son: The Seekers of the Storm final boss, atop Prime Meridian: three phases and a shrinking arena.
Solus Heart: The Alloyed Collective final boss: a fight on floating cubes that keep falling away.
Counting the expansions, 28 bosses: 17 teleporter bosses and the rest special or final.
Sources: the Risk of Rain 2 wiki (each boss page and Module:Enemies/Data, read on 31 October 2026) and the game's own text. The explanations are our own. Icons: Risk of Rain 2 (Hopoo Games / Gearbox).