What the game says, what really changes when you play, and the code to unlock it. Steam says 15.6% of players have it.

Artifact of Dissonance
Game text: «Monsters can appear outside their usual environments.»
Any monster can spawn on any map: Stone Titans on stage one, beetles on the moon. The director picks from every monster in the game.
More varied runs and, early on, more dangerous ones (a golem on stage 1 hurts). It changes everything the combat director picks from the map's list; it does not change fixed spawns (the six that open Mithrix's second phase) or the Void directors (the Reavers of the escape, the Voidling). The Scavenger can show up before looping, and Hermit Crabs never do.
It is in the base game. 15.6% of all Risk of Rain 2 players on Steam have it, from Steam's public stats on 31 October 2026.
Read top to bottom, as shown here: three rows of three shapes. Each slot on the generator changes shape when pressed, in this order: square ■, circle ●, triangle ▲, diamond ♦.
In co-op, the group can enable any artifact that any player has unlocked. Artifacts are chosen in the menu before the run starts.
Enter its code (●■■ / ■■■ / ■■●) in the Compound Generator on Sky Meadow or Helminth Hatchery, use the laptop and beat the Bulwark's Ambry trial: take the key and break the reliquary.
Any monster can spawn on any map: Stone Titans on stage one, beetles on the moon. The director picks from every monster in the game. More varied runs and, early on, more dangerous ones (a golem on stage 1 hurts). It changes everything the combat director picks from the map's list; it does not change fixed spawns (the six that open Mithrix's second phase) or the Void directors (the Reavers of the escape, the Voidling). The Scavenger can show up before looping, and Hermit Crabs never do.
15.6% of all Risk of Rain 2 players on Steam have it, from Steam's public stats on 31 October 2026.
Sources: the game's English text (artifact name and description), the Risk of Rain 2 wiki (riskofrain2.wiki.gg: the Artifacts page and this artifact's page, read on 31 October 2026; code, Compound Generator and Bulwark's Ambry) and public Steam stats. The plain-words text is ours. Icons: Risk of Rain 2 (Hopoo Games / Gearbox).