What the game says, what really changes when you play, and the code to unlock it. Steam says 13.6% of players have it.

Artifact of Chaos
Game text: «Friendly fire is enabled for both survivors and monsters alike.»
Friendly fire for everyone: your attacks hurt your allies and monsters hurt each other. Your own explosions and lightning reach you too.
Solo it is almost an advantage: monsters fight each other and big bosses kill the small ones. In a group, careful with area attacks and the Ukulele.
It is in the base game. 13.6% of all Risk of Rain 2 players on Steam have it, from Steam's public stats on 31 October 2026.
Read top to bottom, as shown here: three rows of three shapes. Each slot on the generator changes shape when pressed, in this order: square ■, circle ●, triangle ▲, diamond ♦.
In co-op, the group can enable any artifact that any player has unlocked. Artifacts are chosen in the menu before the run starts.
Enter its code (●▲● / ●▲● / ●▲●) in the Compound Generator on Sky Meadow or Helminth Hatchery, use the laptop and beat the Bulwark's Ambry trial: take the key and break the reliquary.
Friendly fire for everyone: your attacks hurt your allies and monsters hurt each other. Your own explosions and lightning reach you too. Solo it is almost an advantage: monsters fight each other and big bosses kill the small ones. In a group, careful with area attacks and the Ukulele.
13.6% of all Risk of Rain 2 players on Steam have it, from Steam's public stats on 31 October 2026.
Sources: the game's English text (artifact name and description), the Risk of Rain 2 wiki (riskofrain2.wiki.gg: the Artifacts page and this artifact's page, read on 31 October 2026; code, Compound Generator and Bulwark's Ambry) and public Steam stats. The plain-words text is ours. Icons: Risk of Rain 2 (Hopoo Games / Gearbox).