What the game says, what really changes when you play, and the code to unlock it. Steam says 23.9% of players have it.

Artifact of Sacrifice
Game text: «Monsters drop items on death, but Chests no longer spawn.»
Monsters drop items on death (about 5% each, more for elites and bosses) and chests do not spawn. Printers, shrines and drones still appear.
For fast runs: no chest hunting, just killing. Pairs with the Artifact of Swarms (twice the enemies to kill). Gold piles up: spend it on shrines and drones.
It is in the base game. 23.9% of all Risk of Rain 2 players on Steam have it, from Steam's public stats on 31 October 2026.
Read top to bottom, as shown here: three rows of three shapes. Each slot on the generator changes shape when pressed, in this order: square ■, circle ●, triangle ▲, diamond ♦.
In co-op, the group can enable any artifact that any player has unlocked. Artifacts are chosen in the menu before the run starts.
Enter its code (▲▲▲ / ▲▲▲ / ▲♦▲) in the Compound Generator on Sky Meadow or Helminth Hatchery, use the laptop and beat the Bulwark's Ambry trial: take the key and break the reliquary.
Monsters drop items on death (about 5% each, more for elites and bosses) and chests do not spawn. Printers, shrines and drones still appear. For fast runs: no chest hunting, just killing. Pairs with the Artifact of Swarms (twice the enemies to kill). Gold piles up: spend it on shrines and drones.
23.9% of all Risk of Rain 2 players on Steam have it, from Steam's public stats on 31 October 2026.
Sources: the game's English text (artifact name and description), the Risk of Rain 2 wiki (riskofrain2.wiki.gg: the Artifacts page and this artifact's page, read on 31 October 2026; code, Compound Generator and Bulwark's Ambry) and public Steam stats. The plain-words text is ours. Icons: Risk of Rain 2 (Hopoo Games / Gearbox).