There are over 80 items and 23 tomes. Here are the ones that change a run the most, and every tome, with how they unlock.
About 35 items come unlocked; the rest are earned with challenges and bought with silver. These are the most searched.
When a hit would kill you, it makes you invincible for a few seconds and heals part of your health. The most important item in the game.
Get 3 Leeching Crystals in one run.
More luck: better items and better odds on anything chance-based. Shines with Fox.
One more projectile on every weapon. One of the best for any build.
An extra roll on chance-based on-hit effects (poison, freeze, crit...).
2% of your hits BONK: 20 times the damage.
8% more experience. Good at the start of any run.
Every weapon upgrade offers one extra stat bonus.
Complete 3 challenges.
Your hits can freeze. Freezing 1,000 enemies with it unlocks the Frostwalker.
Your hits can poison: damage over time that works on groups and bosses alike.
Lifesteal that grows with your damage. Three in one run unlock Kevin.
Every so often it pulls in all the experience on the ground.
Complete every Charge Shrine on a map.
20% more damage to nearby enemies.
Kill 5,000 enemies with the Sword.
Lifesteal stacks Bloodmarks, and 50% of your hits mark.
Reach level 50 as Vlad.
Every hit leaves a poison cloud.
Duplicate the Moldy Cheese three times in a row in a Microwave.
A dead companion that helps you. Comes from surviving the Final Swarm.
Survive the Final Swarm for two minutes.
The first 13 come unlocked. The rest are earned with the challenge shown and bought with silver.
More damage. Almost always the first to level; level 7 unlocks Megachad.
Weapons fire more often.
More maximum health.
More movement speed.
Chance to dodge a hit completely.
More critical chance. Level 10 unlocks the Sniper Rifle.
Bigger attacks.
Faster projectiles.
Hits push enemies further.
You regain health over time.
A shield that absorbs a hit and recharges over time.
More gold during the run.
More silver at the end: the tome for faster unlocks.
More experience.
Break 20 pots in a single run.
You take less damage from every hit.
Kill 5,000 enemies as Sir Oofie.
More pickup range for experience.
Use the Shrine of Succ eight times.
Lifesteal. Level 12 unlocks Blood Magic.
Kill 12,500 enemies.
You reflect damage to whoever hits you. Level 9 unlocks Athena.
Block 250 attacks with the Aegis.
Effects last longer.
Upgrade the Axe to level 10.
More projectiles per attack.
Fire 5,000 projectiles.
More luck. Level 12 (with 100 quests) unlocks the Dice and Dicehead.
Dropped by an enemy with a 0.01% chance.
Raises difficulty in exchange for more loot. Do not take it when starting out.
Defeat a stage boss in under five minutes.
Boosts one random stat on every level.
On a Tier 3 run, fully charge every Charge Shrine on all three stages without leaving the zone.
Kevin: when a hit would kill you, it makes you invincible for a few seconds and heals you. It unlocks with 3 Leeching Crystals in one run. Then Backpack (one more projectile on everything) and Clover (luck).
A stat upgrade you level during the run (Damage, Cooldown, HP...). There are 23: 13 come unlocked and the other 10 are earned with challenges. Levels on some tomes unlock characters and weapons.
Common, uncommon, rare, epic and legendary. The rarer, the stronger and the less likely; luck (Clover, Fox, the Luck tome) raises the odds of rare ones.
Sources: the Megabonk community wiki (megabonk.wiki) and public guides (Dexerto, TheGamer, Destructoid, Sportskeeda, games.gg, megabonk.org), as of 1 November 2026. Megabonk changes with every patch: numbers and requirements may vary; when in doubt, the game's Unlocks tab is right. Megabonk is by vedinad; this is fan content.